Graduation Date

Spring 2026

Document Type

Thesis

Program

Master of Arts degree with a major in Psychology, option Academic Research

Committee Chair Name

Carrie Aigner

Committee Chair Affiliation

Cal Poly Humboldt Faculty or Staff

Second Committee Member Name

Mari Sanchez

Second Committee Member Affiliation

Cal Poly Humboldt Faculty or Staff

Third Committee Member Name

Amanda Hahn

Third Committee Member Affiliation

Cal Poly Humboldt Faculty or Staff

Keywords

Open-label placebo, Attention, Expectancy, Pain, Analgesia, Cold-pressor

Subject Categories

Psychology

Abstract

Placebo analgesia has shown promise in treating pain, but practitioners are reluctant to prescribe deceptive placebos. Open-label, or honestly prescribed placebos, offer an ethical alternative. Open-label placebos seem to work largely through experimenter-manipulated expectancy, as well as social/environmental factors. Additionally, verbally guided attention to relevant placebo sensations might bolster pain relief. In the present study, expectancy and attention were experimentally manipulated within a 2 (expectancy: high/low) x 2 (attention: high/low) between-subjects design with a no-treatment comparison group. Pain was experimentally induced in all five experimental groups using the well-established cold pressor task. The primary dependent variables were pain tolerance and pain rating. We hypothesized that high expectancy would result in higher pain tolerance and lower pain rating than low expectancy, and high attention would result in higher pain tolerance and lower pain rating than low attention. Further, high expectancy conditions would display higher pain tolerances and lower pain ratings when they were in the high attention condition compared to the low attention condition. Within a sample size of 91 college students, no significant main effects nor interactions were found for either dependent variable (p’s > .05). However, checks of expectancy indicate that the manipulation      was effective F(1, 69) = 13.89, p< .001, η2 = .17. Implications for future pain and placebo research are discussed.

Citation Style

APA

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