Publication Date
2025
College
College of Natural Resources & Sciences
Department
Chemistry and Biochemistry
Document Type
Poster
Description
Northern Kentucky University conducted a study in which alcoholic drinks mixed with soda & diet soda were drunk, then participants had their BAC measured with a breathalyzer. When the diet soda mixer was used, a higher BAC was measured, indicating faster metabolism. The enzyme, alcohol dehydrogenase, breaks down ethanol, turning it into acetaldehyde with the use of NAD+. If biochemical pathways such as glycolysis are active, the NAD+/NADH ratio will be offset and will limit the process. Since sugar substitutes don't activate glycolysis like sugar, they are essentially inert. I am in the process of determining if the sugar interacts directly with the enzyme to cause this inhibition.