Graduation Date
Fall 2021
Document Type
Thesis
Program
Master of Arts degree with a major in Psychology, option Academic Research
Committee Chair Name
Ethan Gahtan
Committee Chair Affiliation
HSU Faculty or Staff
Second Committee Member Name
Amber Gaffney
Second Committee Member Affiliation
HSU Faculty or Staff
Third Committee Member Name
Christopher Aberson
Third Committee Member Affiliation
HSU Faculty or Staff
Keywords
Neuroscience, Zebrafish, Gcamp, Bpa cyp19, Estrogen, Confocal, Hormones, Neurodevelopment
Subject Categories
Biology
Abstract
The brain is highly dependent on the endocrine system for proper neurodevelopment, as it plays a key role in many biological processes. Bisphenol A is a chemical found in plastics that has the potential to mimic the effects of Estrogen in the body, at least weakly. People interact with plastic that contains BPA regularly, and people are at risk for exposure even before being born. The abundance of BPA, along with other exogenous estrogens, makes examining the relationship between early exposure and changes in brain activity imperative. The current study aims to establish a relationship between disrupted estrogen function and brain activity. Because estrogen receptors are abundantly found in several hypothalamic nuclei, the goal is to specifically examine whether BPA exposure leads to hyperactivity in the hypothalamus, behavioral hyperactivity, and to investigate the impacts on aromatase activity.
Citation Style
APA
Recommended Citation
Dickson, Princess, "Estrogen disruption of hypothalamic neural activity" (2021). Cal Poly Humboldt theses and projects. 517.
https://digitalcommons.humboldt.edu/etd/517
Included in
Behavioral Neurobiology Commons, Biology Commons, Developmental Neuroscience Commons, Endocrinology Commons, Genetics and Genomics Commons, Laboratory and Basic Science Research Commons, Molecular and Cellular Neuroscience Commons, Other Neuroscience and Neurobiology Commons