Graduation Date

Fall 2023

Document Type



Master of Science degree with a major in Kinesiology, option Exercise Science

Committee Chair Name

Taylor Bloedon

Committee Chair Affiliation

HSU Faculty or Staff

Second Committee Member Name

Rock Braithwaite

Second Committee Member Affiliation

HSU Faculty or Staff

Third Committee Member Name

Kari Pilolla

Third Committee Member Affiliation

Community Member or Outside Professional


Menopause, Lipids, Cholesterol, Anthocyanins, Polyphenols, Metabolic syndrome, Cardiometabolic, Inflammation

Subject Categories



Cardiometabolic Diseases (CMDs) are the leading cause of morbidity and mortality among women. During the menopause transition, drops in estrogen play a favorable role in the excess accumulation of Intraabdominal Fat (IAF), altering blood lipid metabolism and inducing inflammatory responses in CMDs attributed to dyslipidemia. This systematic review and meta-analysis examined current research on the effects of whole fruits high in anthocyanins on blood lipid metabolism in women at risk for CMDs. This meta-analysis included 15 studies using the PRISMA 2020 guidelines. Overall, effect sizes were not significant when exploring blood lipid marker outcomes High-Density Lipoprotein (HDL), Low-Density Lipoprotein (LDL), Total Cholesterol (VLDL), and Triglycerides (TGs). However, prediction intervals showed apparent trends between blood lipid means consistent with HDL and TGs but not for VLDL and LDL, suggesting a positive dose-response between whole fruit interventions. Future research should consider establishing standardized protocols for anthocyanin treatment interventions that facilitate the formulation of research-based recommendations with greater ease.

Citation Style




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